IUBMB Lecture

Published: Thursday, 22 December 2016 07:36

IUBMB Lecture will be delivered by Professor François-Xavier Maquart (Unité de Recherche "Matrice Extracellulaire et Dynamique Cellulaire" (MEDyC), UMR CNRS/URCA NO 7369, Faculté de Médecine de Reims, France) under the title "Matrikines as important players in matrix pathobiology".

François-Xavier Maquart, 65, MD, PhD, is professor of biochemistry and molecular biology at the Faculty of Medicine of Reims, France and was the dean of this Faculty from 1997 to 2007. He was the general secretary then president of the French Society of Matrix Biology (1989-1998) and President of the French Collegium of Medical Biochemistry Professors (2003-2009). Since 1997, he is director of the Central Laboratory of Biochemistry of the Reims University Hospital and, since 1995, Director of a Research Unit associated with the CNRS. Since 2008, he also heads a Federative Research Institute which currently groups together 27 research teams. He is a member of the French National Academy of Medicine.

The research activities of François-Xavier Maquart have been focused on the study of cell-extracellular matrix interactions under normal and pathological conditions, particularly tumor invasion and wound healing. He created and developed the concept of "matrikines", peptides derived from the partial degradation of extracellular matrix macromolecules, capable of regulating numerous cellular activities. He characterized several matrikines either activating healing or inhibiting tumor progression, some of which have already been the subject of industrial valorisation. He is co-author of 220 publications indexed in the Web of Science.

Invited Speakers

Published: Thursday, 27 April 2017 08:59

	Name	Address	EXPERTISE AREA
1	Renato V. Iozzo	Department of Pathology, Anatomy & Cell Biology, Thomas Jefferson University, Philadelphia, USA	Proteoglycan biology, cancer and angiogenesis
2	Sylvie Ricard-Blum	University Lyon 1, France	Extracellular matrix interaction networks, matricryptins, glycosaminoglycans, biochemistry, systems biology
3	John R. Couchman	Dept. Biomedical Sciences, University of Copenhagen, Biocenter, Copenhagen, Denmark	Cell adhesion, signaling, cytoskeleton and cell surface proteoglycans
4	Yoshifumi Itoh	The Kennedy Institute of Rheumatology University of Oxford Roosevelt Drive, Headington, Oxford, OX3 7FY, UK	Matrix metalloproteinases, Extracellular matrix, Cell invasion/ migration
5	Liliana Schaefer	Institute of Pharmacology and Toxicology, Goethe University, Frankfurt/Main, Theodor Stern Kai 7, 60590 Frankfurt/Main, Germany	Extracellular matrix, proteoglycans, biglycan, decorin, signaling, inflammation, sepsis, renal diseases, fibrosis
6	Elvira V. Grigorieva	Institute of Molecular Biology and Biophysics, Novosibirsk, Russia; Karolinska Institute, Stockholm, Sweden	Cancer Glycobiology, Extracellular Matrix, Proteoglycan, Heparan Sulfate biosynthesis
7	Paraskevi Heldin	Ludwig Institute for Cancer Research, Uppsala University, Biomedical Center, Uppsala, Sweden	Hyaluronan Biology, Importance of Hyaluronan synthases in cell signaling
8	Raymond Boot-Handford	Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, The University of Manchester, Manchester, UK	Cartilage, growth plate, collagens, ER stress, mouse models of chondrodysplasia
9	Stephane Brezillon	Laboratoire de Biochimie Médicale et Biologie Moléculaire, CNRS UMR 6237, Faculté de Médecine, Université de Reims-Champagne-Ardenne, Reims Cedex, France	Extracellular Matrix biology, Lumican
10	Alberto Passi	Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell'Insubria, Varese, Italy	Extracellular Matrix biology, hyaluronan synthesis
11	Markku Tammi	Institute of Biomedicine/Anatomy, University of Eastern Finland, FI-70211 Kuopio, Finland	Hyaluronan biology
12	Ilona Kovalszky	First Department of Pathology and Experimental Cancer Research, Semmelweis University, H1085 Budapest, Hungary	Oncology, Pathology, Hepatology, Proteoglycans
13	Ralph D. Sanderson	Dept. of Pathology, Univ. Alabama at Birmingham, Alabama, USA	Heparan sulfate and heparanase in cancer biology and therapy
14	Martin Götte	Department of Gynecology and Obstetrics, Muenster University, Medical Center, Muenster, Germany	Proteoglycans, Glycosaminoglycans, microRNA, cancer cell biology
15	Mauro Pavao	Program of Glycobiology, Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Brazil	Glycobiology, proteoglycans, glycosaminoglycans
16	Patricia Rousselle	Biologie Tissulaire et Ingénierie Thérapeutique Department UMR 5305 - CNRS/UCB Lyon 1- SFR BioSciences Gerland-Lyon Sud, France	Cell / ECM interactions, basement membrane, adhesion receptors, syndecans, cytoskeleton, microenvironment
17	Maurizio Onisto	Department of Biomedical Sciences, University of Padova, Italy	Heparanase, cell biology
18	Daniela G. Seidler	Hannover Medical School, Dept. of Gastroentero-, Hepato- and Endocrinology I3, EB2/R3110, Carl-Neuberg-Str. 1, D-30625 Hannover, Germany	Proteoglycans, Glycosaminoglycan synthetic enzymes
19	Geir Christensen	Institute for Experimental Medical Research, University of Oslo, Faculty of Medicine, Norway	ECM and Heart failure
20	Marco Franchi	Faculty of Sciences-University of Bologna, Italy	Ultrastructure of ECM, (SEM)
21	Dimitris Kletsas	Laboratory of Cell proliferation & Ageing, Institute of Biology, National Centre for Scientific Research "Demokritos", Athens, Greece	Age-related pathologies, ECM, growth factors, signaling pathways, stress, wound healing, cancer, stem cells and cell replacement therapy

Senior Speakers (Confirmed)

Published: Friday, 17 February 2017 21:41

	Name	Address	EXPERTISE AREA
1	Sylvie Fournel-Gigleux	UMR 7365 CNRS-Université de Lorraine, Biopôle-Faculté de Médecine, France	Structural biology, GAG synthesizing enzymes
2	Peter Bruckner	Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Germany	Cartilage development and endochondral bone formation
3	Manuel Dauchez	CNRS UMR 7369 MEDyC, University of Reims Champagne-Ardenen, France	Structure/Function/Dynamic Relationships, Protein Protein Interactions, Molecular Modeling, Numerical Simulations, Computational Biolochemistry
4	Nikos Karamanos	Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece	Matrix Molecular Targets in Breast Cancer, Proteoglycans, Metalloproteinases, ER cross-talk signaling
5	Ida Gjervold Lunde	Institute for Experimental Medical Research (IEMR), Oslo University Hospital and University of Oslo, Oslo, Norway	Role of proteoglycans in heart failure
6	Thomas Neill	Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA	Role of decorin in the regulation of mitochondrial autophagy (mitophagy) in cancer
7	Antonio Rossi	Department of Molecular Medicine, Unit of Biochemistry, Pavia, Italy	Biochemical and molecular studies of chondrodysplasias
8	Irit Sagi	Department of Biological Regulation, Weizmann Institute of Science, Israel	Tissue remodeling – from biophysical principles to drug design
9	Rashmin Savani	Department of Pediatrics, Center for Pulmonary &Vascular Biology, University of Texas, USA	Role of Hyaluronan/RHAMM in tissue injury
10	Spyros Skandalis	Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece	Proteoglycans, Hyaluronan/CD44 in Cancer
11	Achilleas Theocharis	Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece	Proteoglycans (serglycin) in multiple myeloma and cancer progression
12	Dimitrios Zeugolis	Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), NUI Galway, Galway, Ireland	Functional biomaterials, Tissue engineering

FEBS Advanced Lecture Course - Matrix Pathobiology, Signaling and Molecular Targets

FEBS-MPST 2017, Spetses , 25th - 30th May

IUBMB Lecture

Invited Speakers

Senior Speakers (Confirmed)