posticon IUBMB Lecture

Published: Thursday, 22 December 2016 07:36 Print Email

IUBMB Lecture will be delivered by Professor François-Xavier Maquart (Unité de Recherche "Matrice Extracellulaire et Dynamique Cellulaire" (MEDyC), UMR CNRS/URCA NO 7369, Faculté de Médecine de Reims, France) under the title "Matrikines as important players in matrix pathobiology".

François-Xavier Maquart, 65, MD, PhD, is professor of biochemistry and molecular biology at the Faculty of Medicine of Reims, France and was the dean of this Faculty from 1997 to 2007. He was the general secretary then president of the French Society of Matrix Biology (1989-1998) and President of the French Collegium of  Medical Biochemistry Professors (2003-2009). Since 1997, he is director of the Central Laboratory of Biochemistry of the Reims University Hospital and, since 1995, Director of a Research Unit associated with the CNRS. Since 2008, he also heads a Federative Research Institute which currently groups together 27 research teams. He is a member of the French National Academy of Medicine.

The research activities of François-Xavier Maquart have been focused on the study of cell-extracellular matrix interactions under normal and pathological conditions,  particularly tumor invasion and wound healing. He created and developed the concept of "matrikines", peptides derived from the partial degradation of extracellular matrix macromolecules, capable of regulating numerous cellular activities. He characterized several matrikines either activating healing or inhibiting tumor progression, some of which have already been the subject of industrial valorisation. He is co-author of 220 publications indexed in the Web of Science.

posticon Invited Speakers

Published: Thursday, 27 April 2017 08:59 Print Email





Renato V. Iozzo

Department of Pathology, Anatomy & Cell Biology, Thomas Jefferson University, Philadelphia, USA

Proteoglycan biology, cancer and angiogenesis


Sylvie Ricard-Blum

University Lyon 1, France

Extracellular matrix interaction networks, matricryptins, glycosaminoglycans, biochemistry, systems biology


John R. Couchman

Dept. Biomedical Sciences, University of Copenhagen, Biocenter, Copenhagen, Denmark

Cell adhesion, signaling, cytoskeleton and cell surface proteoglycans


Yoshifumi Itoh

The Kennedy Institute of Rheumatology
University of Oxford Roosevelt Drive, Headington, Oxford, OX3 7FY, UK

Matrix metalloproteinases, Extracellular matrix, Cell invasion/ migration


Liliana Schaefer

Institute of Pharmacology and Toxicology, Goethe University, Frankfurt/Main, Theodor Stern Kai 7, 60590 Frankfurt/Main, Germany

Extracellular matrix, proteoglycans, biglycan, decorin, signaling, inflammation, sepsis, renal diseases, fibrosis


Elvira V. Grigorieva

Institute of Molecular Biology and Biophysics, Novosibirsk, Russia; Karolinska Institute, Stockholm, Sweden

Cancer Glycobiology, Extracellular Matrix, Proteoglycan, Heparan Sulfate biosynthesis


Paraskevi Heldin

Ludwig Institute for Cancer Research, Uppsala University, Biomedical Center, Uppsala, Sweden

Hyaluronan Biology, Importance of Hyaluronan synthases in cell signaling


Raymond Boot-Handford

Wellcome Trust Centre for Cell-Matrix Research, Faculty of Life Sciences, The University of Manchester, Manchester, UK

Cartilage, growth plate, collagens, ER stress, mouse models of chondrodysplasia


Stephane Brezillon

Laboratoire de Biochimie Médicale et Biologie Moléculaire, CNRS UMR 6237, Faculté de Médecine, Université de Reims-Champagne-Ardenne, Reims Cedex, France

Extracellular Matrix biology, Lumican


Alberto Passi

Dipartimento di Scienze Biomediche Sperimentali e Cliniche, Universita degli Studi dell'Insubria, Varese, Italy

Extracellular Matrix biology, hyaluronan synthesis


Markku Tammi

Institute of Biomedicine/Anatomy, University of Eastern Finland, FI-70211 Kuopio, Finland

Hyaluronan biology


Ilona Kovalszky

First Department of Pathology and Experimental Cancer Research, Semmelweis University, H1085 Budapest, Hungary

Oncology, Pathology, Hepatology, Proteoglycans


Ralph D. Sanderson

Dept. of Pathology, Univ. Alabama at Birmingham, Alabama, USA

Heparan sulfate and heparanase in cancer biology and therapy


Martin Götte

Department of Gynecology and Obstetrics, Muenster University, Medical Center, Muenster, Germany

Proteoglycans, Glycosaminoglycans, microRNA, cancer cell biology


Mauro Pavao

Program of Glycobiology, Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Brazil

Glycobiology, proteoglycans, glycosaminoglycans


Patricia Rousselle

Biologie Tissulaire et Ingénierie Thérapeutique Department UMR 5305 - CNRS/UCB Lyon 1- SFR BioSciences Gerland-Lyon Sud, France

Cell / ECM interactions, basement membrane, adhesion receptors, syndecans, cytoskeleton, microenvironment


Maurizio Onisto

Department of Biomedical Sciences, University of Padova, Italy

Heparanase, cell biology


Daniela G. Seidler

Hannover Medical School, Dept. of Gastroentero-, Hepato- and Endocrinology I3, EB2/R3110, Carl-Neuberg-Str. 1, D-30625 Hannover, Germany

Proteoglycans, Glycosaminoglycan synthetic enzymes


Geir Christensen

Institute for Experimental Medical Research, University of Oslo, Faculty of Medicine, Norway

ECM and Heart failure


Marco Franchi

Faculty of Sciences-University of Bologna, Italy

Ultrastructure of ECM, (SEM)


Dimitris Kletsas

Laboratory of Cell proliferation & Ageing, Institute of Biology, National Centre for Scientific Research "Demokritos", Athens, Greece

Age-related pathologies, ECM, growth factors, signaling pathways, stress, wound healing, cancer, stem cells and cell replacement therapy

posticon Senior Speakers (Confirmed)

Published: Friday, 17 February 2017 21:41 Print Email







Sylvie Fournel-Gigleux

UMR 7365 CNRS-Université de Lorraine, Biopôle-Faculté de Médecine, France

Structural biology, GAG synthesizing enzymes


Peter Bruckner

Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Germany

Cartilage development and endochondral bone formation


Manuel Dauchez

CNRS UMR 7369 MEDyC, University of Reims Champagne-Ardenen, France Structure/Function/Dynamic Relationships, Protein Protein Interactions,  Molecular Modeling, Numerical Simulations, Computational Biolochemistry


Nikos Karamanos

Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece

Matrix Molecular Targets in Breast Cancer, Proteoglycans, Metalloproteinases,

ER cross-talk signaling


Ida Gjervold Lunde

Institute for Experimental Medical Research (IEMR), Oslo University Hospital and University of Oslo, Oslo, Norway

Role of proteoglycans in heart failure


Thomas Neill

Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, USA

Role of decorin in the regulation of mitochondrial autophagy (mitophagy) in cancer


Antonio Rossi

Department of Molecular Medicine, Unit of Biochemistry, Pavia, Italy

Biochemical and molecular studies of chondrodysplasias


Irit Sagi

Department of Biological Regulation, Weizmann Institute of Science, Israel

Tissue remodeling – from biophysical principles to drug design


Rashmin Savani

Department of Pediatrics, Center for Pulmonary &Vascular Biology, University of Texas, USA

Role of Hyaluronan/RHAMM in tissue injury


Spyros Skandalis

Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece

Proteoglycans, Hyaluronan/CD44 in Cancer


Achilleas Theocharis

Laboratory of Biochemistry, Department of Chemistry, University of Patras, Greece

Proteoglycans (serglycin) in multiple myeloma and cancer progression


Dimitrios Zeugolis

Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), NUI Galway, Galway, Ireland

Functional biomaterials, Tissue engineering